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2011 UW Science in Medicine Lecture

Yesterday, I had the honor and privilege of presenting the 2011 Science in Medicine Lecture at the University of Washington School of Medicine. The topic of my presentation was the etiological framework for the assessment and management of obesity.

As regular readers will be well aware, obesity is about far more than simply managing calories in and calories out.

Or, as the organisers of this annual talk so accurately put it:

“As the 2011 UW Science in Medicine Lecturer, Sharma will talk about systemically assessing the effects social, cultural, biomedical, and psychological factors, as well as treatments, such as dieting and drugs for other conditions, have on energy input, metabolism and expenditure. He will discuss factors that affect metabolism – how the body powers its activities and stores energy. Metabolism is influenced by age, gender, genetics, brain hormones, loss of muscle mass and strength, metabolically active fat, medications, and prior weight loss.

He will also look at the many facets of energy intake – social and cultural influences, mindless eating, physical hunger, emotional eating, mental health contributors, and medication. Then, he will examine influences on expending energy through activity – physical and emotional deterants, sociocultural factors, and medications.

Sharma will show how analyzing the framework of contributing factors can help clinicicians systematically assess, identify, and thereby address the specific determinants of an individual patient’s energy balance, including imbalances leading to weight gain. Such an approach could result in more effective prevention and management of obesity.”

Judging by the interest and following discussion, it would be fair to say that the talk was well received.

I am certainly grateful to the University of Washington for bestowing on me this honour and allowing me the opportunity to present my thoughts and research work to my esteemed colleagues here in Seattle.

Seattle, Washington


  1. May I have the honour to send me your lecture and permission to present it to my collaegues in Faculty of medicine , Minia Uninersity,Egypt

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  2. I wish I could have been there!
    I hope you got to enjoy a little late afternoon sunshine yesterday!
    I’m truly grateful that the students and faculty of the school were recipients of your wisdom and perspective.

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  3. I watched it remotely from the South Lake Union Campus of UW. Great talk. I always like to see clinicians acknowledging the homeostatic side of body fat management.

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  4. PS- your edema analogy was great. I’m going to post it on my blog Whole Health Source.

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  5. will this be accessible anywhere? sorry i missed it

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  6. I am so disappointed that I missed this lecture – I live in Seattle and work in the obesity field. I am an admirer of your work! Is there a way to get access to a podcast of this lecture?

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  7. Wow, what expectations! I hope they gave you sufficient time to talk (measured in days).

    Seriously, though, congratulations. How spectacular that a group of influential people are introduced to how complex this field of study/treatment is. Another rock in the pond, the ripples flow outward.

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