How Bariatric Surgery Improves Fatty Liver Disease

Fatty Liver

Fatty Liver

Last week I posted on the importance of non-acoholic fatty liver disease as one of the most common yet insidious consequences of obesity.

Now, a paper by Bower and colleagues from Imperial College London, published in Obesity Surgery, provides a systematic review of the impact of bariatric surgery on liver biochemistry and histology.

The review clearly shows that bariatric surgery is associated with a significant reduction in the steatosis, fibrosis, hepatocyte ballooning and lobular inflammation. Surgery is also associated with a reduction in liver enzyme levels, with statistically significant reductions in ALT, AST, ALP and gamma-GT.

However, there is considerable variability in these outcomes and between different types of interventions – clearly suggesting that more research on this issue is needed.

Nevertheless, at this time it appears that bariatric surgery may well be the most effective treatment for fatty liver disease.

Edmonton, AB