Monday, June 9, 2008

Fracture Non-Union in Obesity

On Saturday (June 7), I presented at a session on How Obesity Affects Orthopaedic Care at the 2nd joint meeting of the American and Canadian Orthopaedic Associatons in Quebec City.

Despite being on the last day of this meeting, the session was surprisingly well attended, probably a reflection of the increasing awareness of issues around orthopaedic care for patients with severe obesity.

While I presented my usual take on how obesity is now a widespread chronic disease, I did take away some interesting aspects related to orthopaedic care of patients with obesity that I was unaware of.

For example, George Russell (Jackson, Mississippi) in his talk mentioned the issue that in severely obese patients immobilization of fractures with a plaster cast poses a significant problem due to the “cushioning” effect of the surrounding adipose tissue. This results in an increased risk of “non-union”, often requiring additional internal or external fixation to ensure healing.

Russell also presented an interesting view of how differences in body fat distribution pose specific problems in orthopedic surgery on hips and knees. Thus, in patients with the “large belly - thin limb” phenotype, the operation on the limbs is relatively easy, but, given the association between large bellies and cardiometabolic risk, these patients are at greater risk for poor wound healing and cardiovascular problems. In contrast, patients with “large limbs - thin bellies” present problems related to the size of the limbs resulting in a greater risk for bleeding and wound infections. Obviously, patients with “large bellies - large limbs” are at increased risk for both types of complications.

In a talk on orthopaedic problems in childhood obesity, Benjamin Alman (Sick Kids, Toronto) mentioned the issue of “relatively” (i.e. in relationship to their body mass) lower bone density in children with overweight and obesity, an issue that may increase the likelihood of traumatic fractures in these kids - again, something I had not previously thought much about.

Bassam Masri (UBC, Vancouver) confirmed that despite slightly greater risk and less functionality following joint replacement in patients with severe obesity, their satisfaction is no smaller than that or non-obese patients - clear indication that obese patients should not be denied surgery simply because of their size. But don’t expect to see spontaneous weight loss after surgery - in fact weight sometimes even goes up in overweight patients following surgery (I have blogged on this before).

I was particularly happy to note that all three surgeons called upon their colleagues to show compassion and deliver care with the same professional attitudes with which they approach their non-obese patients.

Overall, a most interesting session. I am delighted to see the orthopaedic surgeons taking this great interest in this (unfortunately) increasingly important issue.

AMS
Edmonton, Alberta

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Thursday, May 22, 2008

Obesity and Hip Replacements

Overweight and obesity are well-established risk factors for osteoarthritis and a major factor in driving the increasing demand for hip and knee replacements.

How does being overweight or obese affect functional outcomes of hip surgery?

This question was addressed by André Busato and colleagues from the Institute for Evaluative Research in Orthopaedic Surgery, University of Berne, Switzerland in a paper just out in Obesity Surgery.

Busato and colleagues quantified the role of high preoperative BMI on long-term pain status and functional outcome after total hip replacements in a multi-center cohort of 20,553 primary hip replacements (18,968 patients) and 43,562 postoperative clinical examinations for a follow-up period of up to 15 years.

Despite equal pain relief in obese and lean patients, there was an almost perfect dose-effect relationship between preoperative BMI and decreased ambulation during the follow-up period.

This means that despite improvement in pain, patients with higher BMIs tend to regain less mobility following the hip replacement.

While the authors suggest that lifestyle management and pre- or post-surgical weight loss will improve outcomes, this has yet to be demonstrated in a large randomized trial.

It may well be that other factors unrelated to pain may be affecting mobility in heavier patients. In fact many factors that may have led to the weight gain in the first place may not be resolved simply by having a hip replacement.

This observation is not different from that of a previous study that I recently blogged on which reported that back surgery for pain relief in patients with spinal stenosis does not automatically result in increased mobility or weight loss.

Obesity is a multifactorial chronic disease and the long-term impact of educational and behavioural interventions is modest at best.

When present, obesity has to be addressed with the same interdisciplinary acumen and persistence as any other chronic disease.

AMS
Edmonton, Alberta

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In The News

Big waist size nearly doubles risk of early death: Study

Aug. 11, 2010 Vancouver Sun – "What's important is overall mortality," said Dr. Arya Sharma, scientific director of the Canadian Obesity Network. "In the end, having a large waist circumference kills you." Read the article

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