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Do SGLT-2 Inhibitors Change Fat Metabolism?

Since the introduction of SGLT-2 inhibitors (“gliflozins” or “glucoretics), as an insulin-independent treatment for type 2 diabetes, that works by blocking glucose reabsorbtion in the kidney resulting in loss of glucose (and calories) through the kidney, much has been written about the (albeit modest) weight loss associated with this treatment. Several studies have documented tha… Read More »

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Metformin Attenuates Long-Term Weight Gain in Insulin-Resistant Adolescents

The biguanide metformin is widely used for the treatment of type 2 diabetes. Metformin has also been shown to slow the progression from pre to full-blown type 2 diabetes. Moreover, metformin can reduce weight gain associated with psychotropic medications and polycystic ovary syndrome. Now, a randomised controlled trial by M P van der Aa and colleagues from the Netherlands, published in Nutrition &… Read More »

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Can Planned Cheating Help You Stick With Your Diet?

Many diet plans praise the importance of strict adherence to whatever the storyline of the diet happens to be. This includes tips on what foods to avoid or to never eat. Indulging in these “forbidden” foods, is considered cheating and failure. Now, research by Rita Coelho do Vale and colleagues, published in the Journal of Consumer Psychology, explores the notion that planned “ch… Read More »

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Effectiveness of Exercise Interventions After Bariatric Surgery

There is no doubt that exercise is good for you and that individuals with obesity, both before and after bariatric surgery (like everyone else), would stand to benefit from increasing their levels of physical activity. Following bariatric surgery, exercise may be particularly important not just to increase physical fitness, but also to limit the obligatory loss in muscle mass that generally accomp… Read More »

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What Behaviours Are Important For Optimal Outcomes With Bariatric Surgery?

Bariatric surgery is by far the most effective treatment for severe obesity but outcomes vary from one patient to the next. Now a paper by James Mitchell and colleagues, published in JAMA Surgery, reports on the postoperative eating behaviors and weight control strategies that are associated with differences in body weight seen at 3 years after bariatric surgery. The study looks at self-reported d… Read More »

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