Saturday, July 21, 2012

Hindsight: Bariatric Medicine Without Surgery is Like Nephrology Without Dialysis

One of the first articles I wrote after arriving in Canada as Canada Research Chair (Tier 1) in Cardiovascular Obesity Research and Management at McMaster University, was an editorial published in OBESITY SURGERY, in which I expressed my frustration about not having ready access to bariatric surgery for my patients, who desperately needed it.

In this article I noted that

“On accepting the position, I knew that I would be required to do some pioneering work: obesity or rather bariatric medicine is not a ‘recognized’ medical speciality. Rotation in an ‘obesity unit’ is neither a requirement nor of interest to the majority of medical residents. Most doctors’ understanding of obesity, its causes, its complications, and its management is not substantially different from that of a lay person. The well-known bias and discrimination that meets obese patients is also encountered in the commonly held views on the need for and delivery of medical and surgical treatment for this condition.”

“Within weeks of my arrival, referrals for patients began coming in, rapidly growing to over 20 per week. Within a few months, calls were coming in from across the province. One of the first patients I was called to see was a 41-year-old man weighing 436 kg, who had spent the last 9 months in an intensive care unit where he was being treated for intractable lymphedema and cellulitis of his lower extremities. The patient was living in his own ICU suite, while his caregivers were exploring the possibility of having him accepted for obesity surgery. It was already evident that this surgery could not be performed in Canada.”

“Within the first 6 months of my practice, I saw the heaviest people I had ever seen in my life. BMIs >50 kg/m2 were the rule rather than the exception. Most were below the age of 45, virtually none were currently employed, few had drug plans, and none had coverage for antiobesity medication. The majority had a history of childhood-onset obesity, all had significant co-morbidities including diabetes, reflux disease, sleep apnea, and debilitating back and knee pains.

All had significant histories of weight loss attempts, ranging from Weight Watchers and very low- calorie diets to rather questionable ‘medically supervised’ commercial weight loss programs. Many had also failed on pharmacotherapy. None had thus far been offered surgical treatment – the few who had tried to find surgeons in Canada soon discovered that there were only six surgeons performing obesity surgery in the province (population 9,000,000), none of whom were accepting referrals. Some patients were vaguely aware of a process for ‘out-of-province’ referrals, but none knew how to go about it or whom to ask for assistance.

Interestingly, despite the undeniable suffering and disability caused by their excess body weight, a seemingly large proportion of patients would not consider a surgical option because of the perceived risk. They were still hopeful that I would know of some magic bullet that could cure them of their condition (so were some of their referring physicians).”

“Clearly, surgery cannot be a solution for every patient with morbid obesity. Even with 1,000 operations a year, it would take over 200 years to operate on every morbidly obese patient in Ontario. So who should be operated upon, by whom, with what operation, and at what time point in the course of the disorder? Currently, there is little evidence from randomized controlled trials – the ‘gold standard’ of evidence-based medicine – on any of these issues. It appears that the basis for current practice is largely empirical, based on the expertise and judgement of individual surgeons. Yet, an important premise of ‘evidence-based’ medicine is to base care on the best available evidence. If empirical evidence is all we have, then this is what our standard of care should be based on – and no doubt, the empirical data in support of obesity surgery is impressive. It is clearly by far the most, if not the only, successful treatment for morbid obesity currently available.”

“Indeed, without the possibility of referring my patients to an experienced and dedicated obesity surgeon, I feel like I am practising nephrology with no access to dialysis or transplantation. There was only so much I could achieve with diet, blood pressure management, and immunosuppression in my patients with advanced renal failure. In the end, their survival depended on renal replacement therapy.

Similarly, there is only so much I can achieve with diet, exercise, and pharmacotherapy in my morbidly obese patients – ultimately resolution of their medical problems, if not their very survival, will depend on successful obesity surgery. In fact, from all that I have read and seen so far, obesity surgery for morbid (or should we call it malignant?) obesity appears far more successful in terms of improving quality of life, resolving co-morbidities, and promoting physical, mental, and socioeconomic rehabilitation than either hemodialysis or renal transplantation for patients with end-stage renal failure.”

“Surgery remains an important option for numerous ‘medical’ disorders: coronary bypass surgery for coronary artery disease, fundoplication for gastro-esophageal reflux, parathyroidectomy for hyper-parathyroidism, bullectomy for pulmonary bullous emphysema, knee replacements for osteoarthritis, kidney transplantation for renal failure, to name a few. Younger physicians perhaps forget that less than two decades ago, surgery was the treatment of choice for gastric and duodenal ulcers. All of these patients require long-term follow-up and management by internists or family physicians. Recognition of the important role of obesity surgery in the treatment of morbid obesity by internists and family physicians, and their commitment and dedication to the long-term medical management of patients who have undergone bariatric surgery, is long overdue.

For my part, I will undertake all that is necessary to establish bariatric surgery as an important and much needed surgical program at our university medical center.”

A lot has happened since I wrote these words.

Only days after I accepted my current position at the University of Alberta, the Ontario Government did announce funding for a bariatric program at McMaster – too late for me, I had already signed my new contract.

Today, Ontario does have its own Bariatric Network of “Pre-assessment” Clinics and bariatric Centres of Excellence. On the other hand, Ontario has yet to find a model that will appropriately look after the well over 2,000 patients who now receive bariatric surgery each year. There is still no non-surgical program that will treat obese patients early enough to prevent them from reaching a stage where they do need surgery. Nor is there a system in place to manage those who are not good candidates for or do not choose to undergo surgery.

Despite thousands of operations, there is still no real ‘academic’ bariatric program in Ontario – in 2010/11  there was barely a handful of peer-reviewed publications on bariatric care from all of Ontario – not even one paper per medical school – not surprising perhaps, given that there is not even a single chair in bariatric medicine or surgery at any of its five universities.

So, while more patients are now at least getting treatment, the field of bariatric medicine and surgery is still seeking form and structure in Ontario. To be fair, the situation is not that much better in other provinces.

Quebec has seen some improvements in access, but lags well behind Ontario in numbers. Nova Scotia has a fledgling program as does New Brunswick. Saskatchewan and Manitoba now perform a handful of surgeries a year. BC still has no recognizable bariatric strategy.

With about 600 surgeries performed across Alberta together with significant investments into a provincial obesity plan, Alberta, given the size of its population, may be slightly ahead of the pack – at least academically, it ranks number one, if the number of scientific publications on bariatric surgery is any indicator (12 paper in 2011, closely followed by Quebec with 10 articles, easily outranking all of Ontario with a single paper published in 2011).

Thus, eight years after I wrote this editorial, surprisingly little has changed when it comes to the recognition and importance of bariatric care and the need for greater investments and resources into researching the many open questions about the care of these patients.

Across Canada it is still far easier for someone with failing kidneys to receive dialysis than for someone with severe obesity to receive even minimally adequate medical or surgical treatment.

I wonder what the next eight years will bring to the field and to my patients – how much longer are they willing to wait?

AMS
Edmonton, Alberta

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Monday, March 26, 2012

Welcome to the 2nd International School for Obesity Research and Management

This week, we are hosting the 2nd International School for Obesity Research and Management (ISORAM) at the Chateau Fairmont, Lake Louise.

The following is the welcome letter to the delegates of this ‘sold-out’ event::

Welcome to the 2nd International School for Obesity Research and Management, co-hosted by the University of Alberta, the Universität Leipzig, and the Canadian Obesity Network.

This year, the focus is on advances in bariatric care with talks ranging from basic science (genetics, gut transporters, adipose tissue) to lifestyle management (dietary and exercise assessments and prescriptions), from new diagnostic definitions and health economics (obesity staging, etiological assessment, program evaluation) to advanced minimal invasive surgery (robotics, endoluminal surgery and bariatric complications).

The faculty includes over 30 leading researchers and clinicians from Canada and Germany as well as guests from Ireland, Denmark, the UK, and the USA.

ISORAM’12 will be attended by over 50 delegates from five countries and promises to once again be an exciting event that will foster international exchange of best practices and research innovations.

This event is also certain to foster camaraderie, friendship, and international collaborations in the area of bariatric research and practice.

Welcome to Lake Louise!

Arya M. Sharma, Edward Shang, Shahzeer Karmali, Matthias Blueher

I look forward to an exciting week.

AMS
Lake Louise, Alberta

p.s. a listing of the program can be downloaded here

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Monday, October 17, 2011

ISORAM’12: Winter Course in Bariatric Medicine and Surgery

Early this year, as part of the Alberta-Saxony Obesity Research and Training Alliance (ASORTA), we hosted the first International School on Obesity Research and Management (ISORAM).

This event was attended by over 50 faculty and trainees from Alberta and Germany.

In a follow-up to this immensely successful event, we are now planning ISORAM ’12, which will be held from March 25-30, 2012, at the Chateau Lake Louise, in Alberta, Canada.

This time the focus will be on all aspects of metabolic and bariatric research as well as medical and surgical management of patients with severe obesity.

The course is open to all health professionals from around the world, who would like to hone their expertise in bariatric medicine and metabolic surgery.

The program, which will offer more than 40 hrs of teaching and interactive workshops, will also include ample time for informal networking and scientific exchange with the international faculty in the unique picturesque surroundings of one of Canada’s premier ski resorts.

Specifically, ISORAM ’12 has the following objectives:

• To provide participants with a sound understanding of the scientific and methodological issues in bariatric medicine and surgical practices.

• To build participants knowledge in the areas of:

a. Clinical assessment and management of bariatric patients
b. Current best practices in dietary, psychological and behavioural management of bariatric patients
c. Current best practices in patient selection and preparation
d. Current understanding of the biology of metabolic and bariatric surgery patients
e. Interdisciplinary obesity research and practice.

• To educate participants in new developments in:

a. Medical and behavioural management of severe obesity
b. Nutritional and psychosocial complications in bariatric patients
c. Emerging devices in obesity management
d. Rehabilitation issues in bariatric care

• To give participants an understanding of health services/health systems impact on issues related to bariatric care

More information on this event can be here.

Please indicate your interest in learning more about and perhaps participating in this event here.

AMS
Edmonton, Alberta

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Friday, April 29, 2011

Bariatric Research Agenda For Canada

Dr. Yves Bolduc (centre) Quebec Minister for Health and Social Services, Dr. Arya Sharma (left) Scientific Director CON-RCO, Dr. Angelo Tremblay (right) 2011 CON-RCO Distinguished Lecturer Award Recipient at the opening of the 2nd National Obesity Summit, Montreal, QC

Dr. Yves Bolduc (centre) Quebec Minister for Health and Social Services, Dr. Arya Sharma (left) Scientific Director CON-RCO, Dr. Angelo Tremblay (right) 2011 CON-RCO Distinguished Lecturer Award Recipient, at the opening of the 2nd National Obesity Summit, Montreal

Regular readers may recall a previous post on a workshop organised by the Canadian Institutes of Health Research (CIHR) Institute for Nutrition, Metabolism and Diabetes (INMD) and the Canadian Obesity Network held in Montreal last year.

The objectives of this workshop, with experts from across Canada, were to

1. define strengths, gaps, and opportunities in Canadian bariatric care research.

2. develop a Canadian bariatric care research agenda that will ultimately improve
health services available to morbidly obese patients.

3. identify opportunities for international collaboration in the area of bariatric care.

4. engage potential research funders that can support an emerging bariatric care research agenda in Canada.

Yesterday, at the opening of the 2nd National Obesity Summit here in Montreal, CIHR-INMD released the final report from this workshop with the following recommendations for a bariatric research agenda.

The following were the top three research priorities identified in terms of knowledge gaps for bariatric care:

Intervention research: understanding variation in response to treatment intervention, matching treatment to need; phenotyping; complications of care; role of co‐morbidity. Topic areas include research on both children and adults.

Health Services and Health Policy research: understanding optimal systems of care focused on continuity of care and integration of pediatric and adult services (i.e., cradle to grave); medical/surgical/rehabilitation/mental health/self‐care; primary care, including collaborative models and intervention strategies for practitioner and practice change.

Access and barriers to treatment: understanding what brings people to treatment and what are the major barriers; weight bias and discrimination including causal factors, impact, and interventions; evaluation of wait‐list management strategies and decision rules for access to bariatric surgery; understanding factors driving demand; forecasting models based on need and demand analyses and projections.

The following were the top three priorities identified in terms of building Canadian research capacity:

Research consortia/collaborations: includes a shift in emphasis to multi‐site, collaborative studies; database development and other capacity building for longitudinal studies.

Outcome and cost assessment: includes an assessment of metabolic and health outcomes beyond weight reduction, such as effects on blood pressure and glucose levels; longer term outcomes includingeconomic impact assessments of both intervention and systems research.

Qualitative/participatory research: required for an exploration of the patient’s lived experience, empowerment, knowledge base and satisfaction with health services and health service models.

The following were the three themes identified in terms of priorities for knowledge translation:

National strategy and standardization of care: decision‐trees for access to surgery; assessment and outcome measures; waiting list prioritization; guidelines for bariatric care team size and composition; accreditation and evaluation; and remuneration of health care providers for delivery of obesity care.

Environmental scans: assessing “what is out there”, who is doing what beyond surgery; level of collaboration and partnerships; building upon the pediatric scan undertaken in Alberta and the adult scan in Quebec.

Engaging policy makers: improving access to existing data; engaging earlier in the research process, including study design; providing better costing data for the development of relevant business cases, including cost effectiveness of treatment interventions (health costs, productivity).

It is anticipated that CIHR-INMD will now prepare targeted requests for applications to address these identified research and capacity building priorities.

The release of this report certainly demonstrates the intent of CIHR to take the needs of the the bariatric population in Canada very seriously.

Even a quick glance at the research excellence present here at this Summit should certainly reassure CIHR that Canadian researchers are ready and willing to address this important research agenda.

Reader can follow events happening here at Montreal on Twitter #con11

AMS
Montreal, Quebec

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Thursday, December 9, 2010

Developing a Research Agenda for Bariatric Care

This week, I am co-hosting a workshop to develop a research agenda for bariatric care in Canada.

This National Workshop is co-organised by the Canadian Institutes of Health Research’s (CIHR) Institute of Nutrition, Metabolism, and Diabetes (INMD) and the Canadian Obesity Network.

As readers may be well aware, CIHR is the federal agency that funds health research in Canada while the Canadian Obesity Network represents over 5000 researchers, health professionals and other stakeholders working to reduce the mental, physical and economic burden of obesity on Canadian children and adults.

The objective of this workshop are as follows:

1) To identify strengths, gaps and opportunities in Canadian bariatric research.

2) To develop a Canadian bariatric care research agenda that can ultimately improve health services available to obese patients.

3) To identify opportunities for international collaborations in the areas of bariatric care.

4) To engage potential research funders that can support an emerging bariatric care research agenda in Canada.

The 2-day workshop features presentations from Canadian researchers on topics ranging from behavioural, medical and surgical treatments to issues related to health systems and health care delivery for patients with excess weight.

The workshop also specifically addresses some of the ethical, legal and gender barriers to bariatric care as well as the needs of special populations, who may be disproportionately affected by obesity and its many consequences.

But the attendees will also hear from patients, who themselves have had to cope with excess weight and are wiling to share their personal stories, wishes, hopes and needs to inform this important research agenda.

Hopefully, the research themes and topics that will be identified at this workshop will not only lead to new research funding and projects but will ultimately result in addressing the very real needs of the over 11,000,000 Canadian adults and over 1,000,000 Canadian children already suffering the dire consequences of excess weight.

As blogged before, efforts targeted at obesity prevention are unlikely to help the people who already have the problem – they will, unfortunately, need treatments – treatments that will hopefully be based on the best scientific research and evidence.

AMS
Montreal, Quebec

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In The News

Patients find obese doctors less credible

Apr. 18, 2013 – The StarPhoenix: "It's no easier for a doctor to control their weight than anyone else," Dr Sharma added. "But studies show that if you talk about genetics and the complex psychobiology (of weight control), people's weight biases go down." Read more: 

» More news articles...

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